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pentobarbital will reduce the extent or result of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will lower the level or result of siponimod by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of siponimod using a drug that causes mo